As we all know, cartilage is difficult to grow and repair. ELISA kit test research shows that adding a compound to chondrocytes can stimulate the growth of new cartilage and simulate the effects of physical exercise. Cartilage tissue at the knees, shoulders and other joints can act as a buffer to make the limbs move smoothly. Physical exercise can keep cartilage healthy and strong, similar to bones and muscles.
Abnormal stress at the joints can cause many problems, causing pain and even incapacitating people. Excessive use or trauma can damage cartilage tissue, and too little exercise will cause cartilage to shrink. Both of the above conditions are prone to arthritis.
Researchers of the ELISA kit studied chondrocytes at the joints of pigs against TRPV4. TRPV4 is an ion channel rich in chondrocytes, which can be opened under mechanical load. The researchers created mechanical loading conditions for the chondrocytes, allowing the cells to grow new cartilage tissue. Subsequently, they added a compound that blocked TRPV4 to the cells, shutting down the signal of the ion channel, and as a result, the cartilage no longer grew, and the effect of mechanical load disappeared.
ELISA kit studies have shown that cartilage grows more when an activator is added compared to mechanical loading conditions. This shows that chondrocytes sense mechanical load through TRPV4.
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