Ohaus EXPLORER? PRO balance helps obesity research

At the University of Florida, try to determine the relationship between obese pregnant voles and their offspring, and whether high calorie and high fat diets constitute obesity for pups (babies) based on whether and when they start eating high calorie and high fat food For additional risks, Ohaus Explorer Balance plays a key research role.

Ohaus EXPLORER â„¢ PRO balance helps obesity research

Highly-skilled scientists and research assistants conduct psychological research and experiments on laboratory animals in a controlled environment. Laboratory animals are essential in helping people understand human and non-human behaviors. In global research surveys, daily trials are based on improving medical knowledge and developing protocols to deal with and treat diseases and behavioral abnormalities. At the University of Florida Behavioral Neuroscience Laboratory, scientists are conducting experiments to study the biological basis of behavior. By using experimental voles and mice, this laboratory focuses on dietary behavior and its effects on obesity, nicotine addiction, and ethanol (alcohol) intake. Senior bioscientist Kimberly Robertson is a senior scientist responsible for all laboratory experiments. Dr. Neil Rowland is the head of the University ’s Department of Psychology and is responsible for supervising the laboratory. Behavioral neuroscience PhD candidate Annaya Mitra is in charge of directing this research. Annaya Mitra is currently pursuing a master ’s degree in public health. At present, the main research in the laboratory is focused on obesity research. Scientists have focused on this research and realized that two-thirds of people in the United States are considered obese-and this number is still increasing. It is worth noting that the increase in the number of obese mothers is mostly pregnant women who are about to give birth. Using experimental voles, the University of Florida tried to determine the key research role in the relationship between obese pregnant rats and their offspring, and based on whether and when high calories and high fat were introduced into the daily diet, high calorie and high fat diets were Do pups (babies) pose an additional risk of obesity? This study attempts to determine the consequences of pregnancy overnutrition on the metabolism and behavior of young rats (obese mothers). According to Mitra, "In this study, our focus is on the physiological impact of maternal obesity on the fetal development of mice." She is particularly interested in examining the results of this study from a public health, awareness, and educational perspective. Mitra added: "As the number of obese women increases, it will of course lead to an increase in the number of obese pregnant women. The metabolic and behavioral consequences of excessive nutrition during pregnancy will have a major impact on the health and economic conditions of future generations. Based on these findings, one of the main goals of this study is to study the developmental consequences of the high-calorie prenatal environment--for feeding behavior, as well as obesity development and organ-specific pathology in adulthood. " The experiment involved trying to "create" obese mice, imitating a high-fat human diet to formulate a diet for obese mice. "Canteen-style" diets for laboratory mice consist of 60% fatty foods, which are purchased in stores (eg, Vienna sausage and fatty oil-based cheese) or prepared in the laboratory (eg, peanut butter and rat feed mixture) And cookie dough) for circular feeding. As an indispensable tool in the laboratory, Robertson strongly recommends the Ohaus Explorer® Pro balance as "lab application equipment". "We use the Explorer Pro balance in all operations, from weighing the weight of our prepared food ingredients to weighing the food share, weighing at determined intervals before and after eating, weighing the amount eaten by laboratory mice and weighing The weight of the experimental mouse. This scale can complete all weighing, and the accuracy can reach an incredible 0.01 grams. When we look for this type of precision and the higher load capacity that can handle the volume of the mouse, this scale is It is the ideal weighing instrument we are looking for. This weighing instrument is equipped with a trolley and wheels and can be moved to any place where needed. "Psychological research and experiments on laboratory animals in a controlled environment by highly skilled scientists and research assistants, Laboratory animals are essential in helping people understand human and non-human behavior. In global research surveys, daily trials are based on improving medical knowledge and developing protocols to deal with and treat diseases and behavioral abnormalities.

At the University of Florida Behavioral Neuroscience Laboratory, scientists are conducting experiments to study the biological basis of behavior. By using experimental voles and mice, this laboratory focuses on dietary behavior and its effects on obesity, nicotine addiction, and ethanol (alcohol) intake. Senior bioscientist Kimberly Robertson is a senior scientist responsible for all laboratory experiments. Dr. Neil Rowland is the head of the University ’s Department of Psychology and oversees the laboratory. Behavioral neuroscience PhD candidate Annaya Mitra is in charge of directing this research. Annaya Mitra is currently pursuing a master ’s degree in public health.

At present, the main research in the laboratory is focused on obesity research. Scientists have focused on this research and realized that two-thirds of people in the United States are considered obese-and this number is still increasing. It is worth noting that the increase in the number of obese mothers is mostly pregnant women who are about to give birth. Using experimental voles, the University of Florida tried to determine the key research role in the relationship between obese pregnant rats and their offspring, and based on whether and when high calories and high fat were introduced into the daily diet, high calorie and high fat diets were Do pups (babies) pose an additional risk of obesity?

This study attempts to determine the consequences of pregnancy overnutrition on the metabolism and behavior of young rats (obese mothers). According to Mitra, "In this study, our focus is on the physiological impact of maternal obesity on the fetal development of mice." She is particularly interested in examining the results of this study from a public health, awareness, and educational perspective.

Mitra added: "As the number of obese women increases, it will of course lead to an increase in the number of obese pregnant women. The metabolic and behavioral consequences of excessive nutrition during pregnancy will have a major impact on the health and economic conditions of future generations. Based on these findings, one of the main goals of this study is to study the developmental consequences of the high-calorie prenatal environment--for feeding behavior, as well as obesity development and organ-specific pathology in adulthood. " The experiment involved trying to "create" obese mice, imitating a high-fat human diet to formulate a diet for obese mice. "Canteen-style" diets for laboratory mice consist of 60% fatty foods, which are purchased in stores (eg, Vienna sausage and fatty oil-based cheese) or prepared in the laboratory (eg, peanut butter and rat feed mixture) And cookie dough) for circular feeding.

As an indispensable tool in the laboratory, Robertson strongly recommends the Ohaus Explorer® Pro balance as "lab application equipment". "We use the Explorer Pro balance in all operations, from weighing the weight of our prepared food ingredients to weighing the food share, weighing at determined intervals before and after eating, weighing the amount eaten by laboratory mice and weighing The weight of the experimental mouse. This scale can complete all weighing, and the accuracy can reach an incredible 0.01 grams. When we look for this type of precision and the higher load capacity that can handle the volume of the mouse, this scale is It is the ideal weighing instrument we are looking for. This weighing instrument is equipped with a trolley and wheels and can be moved to any place as needed. "

This particular study conducted multiple experiments simultaneously. For example, a group of rats is not fed fat at all-the mother is not obese, and the young rats are only fed with standard rat feed, and the diet does not add fat food. Another group of mice was tested to determine the effects of a high-fat diet on juvenile mice of obese mice mothers. A group of mice was also tested to determine the effect of a high-fat diet on adult pups of mothers of obese rats.

The laboratory also uses the Ohaus Explorer Pro ultra-high sensitivity scale to weigh the small doses of medicines fed to mice in the test to monitor and record the effects of overeating.

The mice in these experiments received different amounts of sugar-fat feed (Crisco butter and sugar mixture) at different time intervals to determine dietary behavior. For example, this is something that the rats really want to eat. If they are always provided, will they eat it all at once or divide it into small doses? If the food is only provided once for a short time, will they eat crazy when it is provided? What is the ratio of the sugar-fat mixture consumed by the rat feed? What is the percentage of the total calorie content of the rat in the sugar-fat mixture?

In this particular experiment, Ohaus Explorer Pro weighed the drug dose to see if the specific drug had an effect on the taste of the sugar-fat mixture. Because the dosage of the drug is determined according to the weight of the mouse, in order to achieve this purpose, the scale used must have a high sensitivity to test the small dose of the drug, which is very important. The laboratory uses the same scale to measure the anorexia drug in the experiment to determine the effect of this drug classification on feeding behavior.

The results of the survey so far show that the offspring of high-fat female rats tend to be heavier than the offspring of low-fat female rats. There is a trend to show that male offspring born to high-fat mother rats adopt a high-fat diet after weaning. Compared with young rats born to low-fat mother rats after weaning to a low-fat diet, the stress response of male offspring born to high-fat mother rats is greater . The offspring of rats fed high-fat foods (cookie dough, peanut butter, condensed milk, lard, processed cheese products, canned foods, and sausages) showed higher levels of leptin (proteins produced by fat cells, involved in regulating food intake and body fat Storage) and the trend of higher insulin levels.

Mitra concluded: "In addition to this, we also evaluate the difference in the motivation to obtain food. Our hypothesis is that the offspring fed on a high-fat diet will lack the motivation to work for delicious food, while the offspring fed on a low-fat diet will have greater Motivation. "

The type of research conducted by the University of Florida Behavioral Neuropsychology Laboratory is groundbreaking and is critical for understanding human eating habits, obesity and addiction. Ohaus Weighing Apparatus provides various services for this laboratory and is an important part of every experiment conducted by the laboratory.

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This Ohaus balance is suitable for any laboratory needs.

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